業績

英文業績(研究論文)分野別一覧

英文業績の分野別一覧は、現在工事中につき、下記を参照ください。
https://www.ncbi.nlm.nih.gov/pubmed/?term=ishigatsubo

HO関連

  • HO-1 inhibits IL-13-induced goblet cell hyperplasia associated with CLCA1 suppression in normal human bronchial epithelial cells.
    Mishina K, Shinkai M, Shimokawaji T, Nagashima A, Hashimoto Y, Inoue Y, Inayama Y, Rubin BK, Ishigatsubo Y, Kaneko T.
    Int Immunopharmacol. 2015 Dec 29(2):448-53.

    Pubmed

  • Serum heme oxygenase-1 as a marker of lung function decline in patients with chronic silicosis.
    Sato T, Saito Y, Inoue S, Shimosato T, Takagi S, Kaneko T, Ishigatsubo Y.
    J Occup Environ Med. 2012 Dec;54(12):1461-6.

    Pubmed

  • Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways.
    Hama M, Kirino Y, Takeno M, Takase K, Miyazaki T, Yoshimi R, Ueda A, Itoh-Nakadai A, Muto A, Igarashi K, Ishigatsubo Y.
    Arthritis Rheum. 2012 May;64(5):1518-28
    ≫Supplement (Bach1 regulates osteoclastogenesis via both heme oxygenase-1 dependent and independent pathways.)

    Pubmed

  • Expression of heme oxygenase-1 in human leukemic cells and  its regulation by transcriptional repressor Bach1.
    Miyazaki T, Kirino Y,Takeno M, Samukawa S, Hama M,Tanaka M,Yamaji S,Ueda A,Tomita N,Fujita H,Ishigatsubo Y.
    Cancer Sci. 2010 Jun;101(6):1409-16.

    Pubmed

  • Serum HO-1 is useful to make differential diagnosis of secondary hemophagocytic syndrome from other similar hematological conditions.
    Miyazaki T, Kirino Y, Takeno M, Hama M, Ushihama A, Watanabe R, Takase K, Tachibana T, Matsumoto K, Tanaka M, Yamaji S, Ideguchi H, Tomita N, Fujita H, Ohno S, Ueda A, Ishigatsubo Y.
    Int J Hematol. 2010 Mar;91(2):229-37.

    Pubmed

  • Therapeutic neovascularization by the implantation of autologous mononuclear  cells in patients with connective tissue diseases.
    Takahashi M, Izawa A, Ishigatsubo Y, Fujimoto K, Miyamoto M, Horie T, Aizawa Y, Amano J, Minota S, Murohara T, Matsubara H, Ikeda U.
    Curr Pharm Des. 2009;15(24):2778-83.

    Pubmed

  • Inhibition of heme oxygenase-1 with an epidermal growth factor receptor inhibitor and cisplatin decreases proliferation of lung cancer A549 cells.
    Kuroda H, Takeno M, Murakami S, Miyazawa N, Kaneko T, Ishigatsubo Y.
    Lung Cancer. 2010 Jan;67(1):31-6.

    Pubmed

  • Circulating carbon monoxide level is elevated after sleep in patients with obstructive sleep apnea.
    Kobayashi M, Miyazawa N, Takeno M, Murakami S, Kirino Y, Okouchi A, Kaneko T, Ishigatsubo Y.
    Chest. 2008 Nov;134(5):904-10.

    Pubmed

  • Heme oxygenase 1 attenuates the development of atopic dermatitis-like lesions in mice: Implications for human disease.
    Kirino M, Kirino Y,Takeno M,Nagashima Y,Takahashi K, Kobayashi M,Murakami S,Hirasawa T,Ueda A,Aihara M,Ikezawa Z, Ishigatsubo Y.
    J Allergy Clin Immunol. 2008 Aug;122(2):290-7, 297.e1-8.

    Pubmed

  • Association of reduced heme oxygenase-1 with excessive Toll-like receptor 4 expression in peripheral blood mononuclear cells in Behcet's disease.
    Kirino Y, Takeno M, Watanabe R, Murakami S, Kobayashi M, Ideguchi H, Ihata A, Ohno S, Ueda A, Mizuki N, Ishigatsubo Y.
    Arthritis Res Ther. 2008;10(1):R16.          

    Pubmed

  • Tumor necrosis factor alpha acceleration of inflammatory responses by down-regulating heme oxygenase 1 in human peripheral monocytes.
    Kirino Y, Takeno M, Murakami S, Kobayashi M, Kobayashi H, Miura K,
    Ideguchi H, Ohno S, Ueda A, Ishigatsubo Y.
    Arthritis Rheum. 2007 Feb;56(2):464-75.            

    Pubmed

  • Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury.
    Sato T, Takeno M, Honma K, Yamauchi H, Saito Y, Sasaki T, Morikubo H, Nagashima Y, Takagi S, Yamanaka K, Kaneko T, Ishigatsubo Y.
    Am J Respir Crit Care Med. 2006 Oct 15;174(8):906-14.

    Pubmed

  • Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis.
    Kobayashi H, Takeno M, Saito T, Takeda Y, Kirino Y, Noyori K, Hayashi T, Ueda A, Ishigatsubo Y.
    Arthritis Rheum. 2006 Apr;54(4):1132-42.

    Pubmed

  • Heme oxygenase-1 inhibits cigarette smoke-induced increase in the tracheal mucosal permeability in guinea pigs in vivo.
    Tagawa A, Kaneko T, Shinohara T, Ueda A, Sato T, Ishigatsubo Y.
    Inflamm Res. 2005 May;54(5):229-34.

    Pubmed

  • Increased serum HO-1 in hemophagocytic syndrome and adult-onset Still's disease: use in the differential diagnosis of hyperferritinemia.
    Kirino Y, Takeno M, Iwasaki M, Ueda A, Ohno S, Shirai A, Kanamori H, Tanaka K, Ishigatsubo Y.
    Arthritis Res Ther. 2005;7(3):R616-24.

    Pubmed

  • Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lungs attenuates elastase-induced pulmonary emphysema in mice.
    Shinohara T, Kaneko T, Nagashima Y, Ueda A, Tagawa A, Ishigatsubo Y.
    Hum Gene Ther. 2005 Mar;16(3):318-27.

    Pubmed

  • Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody.
    Takeda Y, Takeno M, Iwasaki M, Kobayashi H, Kirino Y, Ueda A, Nagahama K, Aoki I, Ishigatsubo Y.
    Clin Exp Immunol. 2004 Nov;138(2):237-44.

    Pubmed

  • Pseudomonas aeruginosa-induced neutrophilic lung inflammation is attenuated by adenovirus-mediated transfer of the heme oxygenase 1 cDNA in mice.
    Tsuburai T, Kaneko T, Nagashima Y, Ueda A, Tagawa A, Shinohara T, Ishigatsubo Y.
    Hum Gene Ther. 2004 Mar;15(3):273-85.

    Pubmed

  • Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway.
    Tsuburai T, Suzuki M, Nagashima Y, Suzuki S, Inoue S, Hasiba T, Ueda A, Ikehara K, Matsuse T, Ishigatsubo Y.
    Hum Gene Ther. 2002 Nov 1;13(16):1945-60.

    Pubmed

  • Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice.
    Hashiba T, Suzuki M, Nagashima Y, Suzuki S, Inoue S, Tsuburai T, Matsuse T, Ishigatubo Y.
    Gene Ther. 2001 Oct;8(19):1499-507.
  • Transfer of heme oxygenase 1 cDNA by a replication-deficient adenovirus enhances interleukin 10 production from alveolar macrophages that attenuates lipopolysaccharide-induced acute lung injury in mice.
    Inoue S, Suzuki M, Nagashima Y, Suzuki S, Hashiba T, Tsuburai T, Ikehara K, Matsuse T, Ishigatsubo Y.
    Hum Gene Ther. 2001 May 20;12(8):967-79.

    Pubmed

  • Gene therapy for lung diseases: development in the vector biology and novel concepts for gene therapy applications.
    Suzuki M, Matsuse T, Isigatsubo Y.
    Curr Mol Med. 2001 Mar;1(1):67-79.
  • Immune responses against replication-deficient adenovirus inhibit ovalbumin-specific allergic reactions in mice.
    Suzuki M, Suzuki S, Yamamoto N, Komatsu S, Inoue S, Hashiba T, Nishikawa M, Ishigatsubo Y.
    Hum Gene Ther. 2000 Apr 10;11(6):827-38.

    Pubmed

Affixin関連

  • Prognostic value of integrin beta1-ILK-pAkt signaling pathway in non-small cell lung cancer. 
    Okamura M, Yamaji S, Nagashima Y, Nishikawa M, Yoshimoto N, Kido Y, Iemoto Y, Aoki I, Ishigatsubo Y.
    Hum Pathol. 2007 Jul;38(7):1081-91.

    Pubmed

  • The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction.
    Yoshimi R, Yamaji S, Suzuki A, Mishima W, Okamura M, Obana T, Matsuda C, Miwa Y, Ohno S, Ishigatsubo Y.
    J Immunol. 2006 Mar 15;176(6):3611-24.

    Pubmed

  • Up-regulation of integrin-linked kinase activity in rat mesangioproliferative glomerulonephritis.
    Kagami S, Shimizu M, Kondo S, Kitamura A, Urushihara M, Takamatsu M, Yamaji S, Ishigatsubo Y, Kawachi H, Shimizu F.
    Life Sci. 2006 Mar 13;78(16):1794-800.

    Pubmed

  • Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.
    Yamaji S, Suzuki A, Kanamori H, Mishima W, Yoshimi R, Takasaki H, Takabayashi M, Fujimaki K, Fujisawa S, Ohno S, Ishigatsubo Y.
    J Cell Biol. 2004 May 24;165(4):539-51.

    Pubmed

  • The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.
    Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S, Ishigatsubo Y.
    Genes Cells. 2004 Mar;9(3):193-204.

    Pubmed

  • Possible role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation.
    Yamaji S, Suzuki A, Kanamori H, Mishima W, Takabayashi M, Fujimaki K, Tomita N, Fujisawa S, Ohno S, Ishigatsubo Y.
    Biochem Biophys Res Commun. 2002 Oct 11;297(5):1324-31.

    Pubmed

  • A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction.
    Yamaji S, Suzuki A, Sugiyama Y, Koide Y, Yoshida M, Kanamori H, Mohri H, Ohno S, Ishigatsubo Y.
    J Cell Biol. 2001 Jun 11;153(6):1251-64.

    Pubmed

RamBPM関連

  • Armadillo Repeat Containing 8alpha Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins.
    Tomaru K, Ueda A, Suzuki T, Kobayashi N, Yang J, Yamamoto M, Takeno M, Kaneko T, Ishigatsubo Y.
    Open Biochem J. 2010 Jan 13;4:1-8.

    Pubmed

  • Proteasome-dependent degradation of alpha-catenin is regulated by interaction with ARMc8alpha.
    Suzuki T, Ueda A, Kobayashi N, Yang J, Tomaru K, Yamamoto M, Takeno M, Ishigatsubo Y.
    Biochem J. 2008 May 1;411(3):581-91.

    Pubmed

  • RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex.
    Kobayashi N, Yang J, Ueda A, Suzuki T, Tomaru K, Takeno M, Okuda K, Ishigatsubo Y.
    Gene. 2007 Jul 15;396(2):236-47.

    Pubmed

  • Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM.
    Ideguchi H, Ueda A, Tanaka M, Yang J, Tsuji T, Ohno S, Hagiwara E, Aoki A, Ishigatsubo Y. 
    Biochem J. 2002 Oct 1;367(Pt 1):87-95.

    Pubmed

  • Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1.
    Tanaka M, Ueda A, Kanamori H, Ideguchi H, Yang J, Kitajima S, Ishigatsubo Y.
    J Biol Chem. 2002 Mar 22;277(12):10719-26.

    Pubmed

CpG関連

  • Intrapulmonary Delivery of CpG Microparticles Eliminates Lung Tumors.
    Sato T, Shimosato T, Ueda A, Ishigatsubo Y, Klinman DM.
    Mol Cancer Ther. 2015 Oct 14(10):2198-205.

    Pubmed

  • Therapeutic effect of CpG motifs on the development of chronic graft-versus-host disease in mice.
    Senuma A, Hagiwara E, Nagahama K, Okuda K, Nakamura M, Fukumoto N, Shirai A, Tani K, Ishigatsubo Y.
    Cytokine. 2002 Oct 7;20(1):23-9.

    Pubmed

  • Positive and negative regulatory elements contribute to CpG oligonucleotide-mediated regulation of human IL-6 gene expression.
    Takeshita F, Ishii KJ, Ueda A, Ishigatsubo Y, Klinman DM.
    Eur J Immunol. 2000 Jan;30(1):108-16.

    Pubmed

ベーチェット病関連

  • Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behcet's disease susceptibility.
    Takeuchi M, Mizuki N, Meguro A, Ombrello MJ, Kirino Y, Satorius C, Le J, Blake M, Erer B, Kawagoe T, Ustek D, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Sousa I, Davatchi F, Francisco V, Shahram F, Abdollahi BS, Nadji A, Shafiee NM, Ghaderibarmi F, Ohno S, Ueda A, Ishigatsubo Y, Gadina M, Oliveira SA, Gul A, Kastner DL, Remmers EF.
    Nat Genet. 2017 Feb 6. doi: 10.1038/ng.3786. [Epub ahead of print]

    Pubmed

  • Targeted resequencing implicates the familial Mediterranean fever gene MEFV and the toll-like receptor 4 gene TLR4 in Behcet disease.
    Kirino Y, Zhou Q, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Ugurlu S, Erer B, Abaci N, Ustek D, Meguro A, Ueda A, Takeno M, Inoko H, Ombrello MJ, Satorius CL, Maskeri B, Mullikin JC, Sun HW, Gutierrez-Cruz G, Kim Y, Wilson AF, Kastner DL, Gul A, Remmers EF.
    Proc Natl Acad Sci U S A. 2013 May 14;110(20):8134-9.

    Pubmed

  • Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B*51 and ERAP1.
    Kirino Y, Bertsias G, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, Ozyazgan Y, Sacli FS, Erer B, Inoko H, Emrence Z, Cakar A, Abaci N, Ustek D, Satorius C, Ueda A, Takeno M, Kim Y, Wood GM, Ombrello MJ, Meguro A, Gul A, Remmers EF, Kastner DL.
    Nat Genet. 2013 Feb;45(2):202-7.

    Pubmed

  • Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci.
    Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H.
    Nat Genet. 2010 Aug;42(8):703-6.

    Pubmed

  • Cytokine production profile in patients with Behcet's disease treated with infliximab.                      
    Misumi M, Hagiwara E, Takeno M, Takeda Y, Inoue Y, Tsuji T, Ueda A, Nakamura S, Ohno S, Ishigatsubo Y.
    Cytokine. 2003 Dec 7;24(5):210-8.

    Pubmed

感染症関連

  • Role of MexZ and PA5471 in transcriptional regulation of mexXY in Pseudomonas aeruginosa.
    Yamamoto M, Ueda A, Kudo M, Matsuo Y, Fukushima J, Nakae T, Kaneko T, Ishigatsubo Y.
    Microbiology. 2009 Oct;155(Pt 10):3312-21.

    Pubmed

  • Screening of tuberculosis by interferon-gamma assay before biologic therapy for rheumatoid arthritis.
    Murakami S, Takeno M, Kirino Y, Kobayashi M, Watanabe R, Kudo M, Ihata A, Ueda A, Ohno S, Watanuki Y, Kaneko T, Ishigatsubo Y.
    Tuberculosis (Edinb). 2009 Mar;89(2):136-41.

    Pubmed

  • Net positive charge of HIV-1 CRF01_AE V3 sequence regulates viral sensitivity to humoral immunity.
    Naganawa S, Yokoyama M, Shiino T, Suzuki T, Ishigatsubo Y, Ueda A, Shirai A, Takeno M, Hayakawa S, Sato S, Tochikubo O, Kiyoura S, Sawada K, Ikegami T, Kanda T, Kitamura K, Sato H.
    PLoS One. 2008 Sep 12;3(9):e3206.

    Pubmed

TRIMおよびその他

  • Dysfunction of TRIM21 in interferon signature of systemic lupus erythematosus.
    Kamiyama R, Yoshimi R, Takeno M, Iribe Y, Tsukahara T, Kishimoto D, Kunishita Y, Sugiyama Y, Tsuchida N, Nakano H, Minegishi K, Tamura M, Asami Y, Kirino Y, Ishigatsubo Y, Ozato K, Nakajima H.
    Mod Rheumatol. 2018 Nov;28(6):993-1003.

    Pubmed

  • Suppressive oligodeoxynucleotides synergistically enhance antiproliferative effects of anticancer drugs in A549 human lung cancer cells.
    Takahashi R, Sato T, Klinman DM, Shimosato T, Kaneko T, Ishigatsubo Y.
    Int J Oncol. 2013 Feb;42(2):429-36.

    Pubmed

  • Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus.
    Yoshimi R, Ishigatsubo Y, Ozato K.
    Int J Rheumatol. 2012;2012:718237.

    Pubmed

  • Clinical and pathological roles of Ro/SSA autoantibody system.
    Yoshimi R, Ueda A, Ozato K, Ishigatsubo Y.
    Clin Dev Immunol. 2012;2012:606195. Epub 2012 Dec 6.

    Pubmed

  • The therapeutic effect of rituximab on CD5-positive and CD5-negative diffuse large B-cell lymphoma.
    Hyo R, Tomita N, Takeuchi K, Aoshima T, Fujita A, Kuwabara H, Hashimoto C, Takemura S, Taguchi J, Sakai R, Fujita H, Fujisawa S, Ogawa K, Motomura S, Suzuki R, Ishigatsubo Y.
    Hematol Oncol. 2010 Mar;28(1):27-32.

    Pubmed

  • Diffuse large B cell lymphoma without immunoglobulin light chain restriction by flow cytometry.
    Tomita N, Takeuchi K, Hyo R, Hashimoto C, Takemura S, Taguchi J, Fujita H, Fujisawa S, Ogawa K, Motomura S, Ishigatsubo Y.
    Acta Haematol. 2009;121(4):196-201.

    Pubmed

  • A possible association between the presence of interleukin-4-secreting cells and a reduction in the risk of acute graft-versus-host disease.
    Takabayashi M, Kanamori H, Takasaki H, Yamaji S, Koharazawa H, Taguchi J, Tomita N, Fujimaki K, Fujisawa S, Maruta A, Ishigatsubo Y.
    Exp Hematol. 2005 Feb;33(2):251-7.

    Pubmed

  • Cigarette smoke increases mucosal permeability in guinea pig trachea via tachykinin NK2 receptor activation.
    Tagawa A, Kaneko T, Nishiyama H, Shinohara T, Sato T, Geppetti P, Ishigatsubo Y.
    Eur J Pharmacol. 2005 Jan 10;507(1-3):223-8.

    Pubmed

  • Long-term induction of beta-CGRP mRNA in rat lungs by allergic inflammation.
    Tsukiji J, Sango K, Udaka N, Kageyama H, Ito T, Saito H, Horie H, Inoue S, Kitamura H, Hagiwara E, Ikeda H, Okubo T, Ishigatsubo Y.
    Life Sci. 2004 Nov 26;76(2):163-77.

    Pubmed

  • Therapeutic effect of CpG motifs on the development of chronic graft-versus-host disease in mice.
    Senuma A, Hagiwara E, Nagahama K, Okuda K, Nakamura M, Fukumoto N, Shirai A, Tani K, Ishigatsubo Y.
    Cytokine. 2002 Oct 7;20(1):23-9.

    Pubmed

  • Diabetes is not a potent inducer of neuronal cell death in mouse sensory ganglia, but it enhances neurite regeneration in vitro.
    Sango K, Horie H, Saito H, Ajiki K, Tokashiki A, Takeshita K, Ishigatsubo Y, Kawano H, Ishikawa Y.
    Life Sci. 2002 Oct 4;71(20):2351-68.

    Pubmed

  • Over-expression of PAR-3 suppresses contact-mediated inhibition of cell migration in MDCK cells.
    Mishima A, Suzuki A, Enaka M, Hirose T, Mizuno K, Ohnishi T, Mohri H, Ishigatsubo Y, Ohno S.
    Genes Cells. 2002 Jun;7(6):581-96.

    Pubmed

  • Analysis of exhaled nitric oxide by the helium bolus method.
    Shinkai M, Suzuki S, Miyashita A, Kobayashi H, Okubo T, Ishigatsubo Y.
    Chest. 2002 Jun;121(6):1847-52.

    Pubmed

  • Trachea enhances neurite regeneration from adult rat nodose ganglia in vitro.
    Saito H, Sang K, Horie H, Takeshita K, Ikeda H, Ishigatsubo Y, Ishikawa Y.
    Life Sci. 2002 Mar 8;70(16):1935-46.

    Pubmed

  • Tachykinins via Tachykinin NK(2) receptor activation mediate ozone-induced increase in the permeability of the tracheal mucosa in guinea-pigs.
    Fu L, Kaneko T, Ikeda H, Nishiyama H, Suzuki S, Okubo T, Trevisani M, Geppetti P, Ishigatsubo Y.
    Br J Pharmacol. 2002 Mar;135(5):1331-5.

    Pubmed

  • Cigarette smoking depletes cells spontaneously secreting Th(1) cytokines in the human airway.
    Hagiwara E, Takahashi KI, Okubo T, Ohno S, Ueda A, Aoki A, Odagiri S, Ishigatsubo Y.
    Cytokine. 2001 Apr 21;14(2):121-6.

    Pubmed

  • Nucleotide sequence analysis of the approximately 35-kb segment containing interferon-gamma-inducible mouse proteasome activator genes.
    Yawata M, Murata S, Tanaka K, Ishigatsubo Y, Kasahara M.
    Immunogenetics. 2001 Mar;53(2):119-29.

    Pubmed

  • IL-12-encoding plasmid has a beneficial effect on spontaneous autoimmune disease in MRL/MP-lpr/lpr mice.
    Hagiwara E, Okubo T, Aoki I, Ohno S, Tsuji T, Ihata A, Ueda A, Shirai A, Okuda K, Miyazaki J, Ishigatsubo Y.
    Cytokine. 2000 Jul;12(7):1035-41.

    Pubmed

  • Enhanced neural regeneration from transected vagus nerve terminal in diabetic mice in vitro.
    Saito H, Sango K, Horie H, Ikeda H, Ishigatsubo Y, Ishikawa Y,  Inoue S.
    Neuroreport. 1999 Apr 6;10(5):1025-8.

    Pubmed

  • Administration of an IL-12-encoding DNA plasmid prevents the development of chronic graft-versus-host disease (GVHD).
    Okubo T, Hagiwara E, Ohno S, Tsuji T, Ihata A, Ueda A, Shirai A, Aoki I, Okuda K, Miyazaki J, Ishigatsubo Y.
    J Immunol. 1999 Apr 1;162(7):4013-7.

    Pubmed

  • Altered frequency of type 1 cytokine secreting cells in the peripheral blood of patients with primary Sjogren's syndrome.
    Hagiwara E, Pando J, Ishigatsubo Y, Klinman DM.
    J Rheumatol. 1998 Jan;25(1):89-93.

    Pubmed

  • Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity.
    Ueda A, Ishigatsubo Y, Okubo T, Yoshimura T.
    J Biol Chem. 1997 Dec 5;272(49):31092-9.

    Pubmed

  • Effect of mizoribine on pulmonary lesions in MRL/lpr/lpr mice.
    Soga T, Ishigatsubo Y, Kitamura H, Okubo T.
    Autoimmunity. 1996;25(1):9-18.

    Pubmed

  • Phenotype and frequency of cells secreting IL-2, IL-4, IL-6, IL-10, IFN and TNF-alpha in human peripheral blood.
    Hagiwara E, Abbasi F, Mor G, Ishigatsubo Y, Klinman DM.
    Cytokine. 1995 Nov;7(8):815-22.

    Pubmed

  • Increased utilization of polyreactive B cells during periods of generalized immune activation.
    Ishigatsubo Y, Steinberg AD, Krieg A, Klinman DM.
    Autoimmunity. 1995;22(2):113-9.

    Pubmed

  • Cross-reactivity of IgM- and IgG-secreting B cells in murine chronic graft-versus-host reaction.
    Igarashi T, Ishigatsubo Y, Ohno S, Shirai A, Aoki I, Okubo T, Klinman DM.
    Clin Immunol Immunopathol. 1994 Sep;72(3):307-11.

    Pubmed

  • NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene.
    Ueda A, Okuda K, Ohno S, Shirai A, Igarashi T, Matsunaga K, Fukushima J, Kawamoto S, Ishigatsubo Y, Okubo T.
    J Immunol. 1994 Sep 1;153(5):2052-63.

    Pubmed

  • Human monocyte chemoattractant protein-1 expressed in a baculovirus system.
    Ueda A, Kawamoto S, Igarashi T, Ishigatsubo Y, Tani K, Okubo T, Okuda K.
    Gene. 1994 Mar 25;140(2):267-72.

    Pubmed

  • Polyclonal B cell activation and B cell cross-reactivity during autoantibody production in systemic lupus erythematosus.
    Klinman DM, Shirai A, Ishigatsubo Y.
    Adv Exp Med Biol. 1994;347:115-23.

    Pubmed

  • Cross-reactivity of IgM- and IgG-secreting B cells in autoimmune mice.
    Ishigatsubo Y, Igarashi T, Ohno S, Ueda A, Okubo T, Klinman DM.
    Arthritis Rheum. 1993 Jul;36(7):1003-6.

    Pubmed

  • Polyclonal B cell activation and antigen-specific stimulation in mice with chronic graft-versus-host reaction.
    Aoki A, Ishigatsubo Y, Hagiwara E, Shirai A, Igarashi T, Tani K, Maruta A, Otani M, Aoki I, Misugi K, et al.
    Clin Immunol Immunopathol. 1993 Mar;66(3):254-9.

    Pubmed

  • Glomerulonephritis induced by murine chronic graft-versus-host reaction.
    Otani M, Aoki I, Miyagi Y, Misugi K, Aoki A, Hagiwara E, Tani K, Ishigatsubo Y, Okubo T.
    Acta Pathol Jpn. 1992 May;42(5):325-32.

    Pubmed

  • A correlation between IgG class antibody production and glomerulonephritis in the murine chronic graft-versus-host reaction.
    Aoki I, Aoki A, Otani M, Miyagi Y, Misugi K, Ishii N, Hagiwara E, Tani K, Okubo T, Ishigatsubo Y.
    Clin Immunol Immunopathol. 1992 Apr;63(1):34-8.

    Pubmed

  • Increase in intracellular calcium induced by stimulating histamine H1 receptors in macrophage-like P388D1 cells.
    Ohno S, Shirai A, Ueda A, Igarashi T, Ishigatsubo Y, Tani K, Okubo T, Hikawa N, Kawakami T, Takenaka T.
    Biochem Biophys Res Commun. 1991 Dec 31;181(3):1156-63.

    Pubmed

  • Quantitation of IgM- and IgG-secreting B cells in the peripheral blood of patients with systemic lupus erythematosus.
    Klinman DM, Shirai A, Ishigatsubo Y, Conover J, Steinberg AD.
    Arthritis Rheum. 1991 Nov;34(11):1404-10.

    Pubmed

  • Preferential proliferation of anti-DNA producing cells of NZB mice in NZB.xid recipients.
    Hagiwara E, Ishigatsubo Y, Aoki A, Shirai A, Tani K, Okubo T.
    Autoimmunity. 1991;9(2):123-9.

    Pubmed

  • Quantitation of autoantibody-secreting B cells in systemic lupus erythematosus.                                                                
    Ishigatsubo Y, Sakamoto H, Hagiwara E, Aoki A, Shirai A, Tani K, Okubo T, Klinman DM.
    Autoimmunity. 1989;5(1-2):71-8.

    Pubmed

  • Studies on the influence of the internal environment on autoantibody production by B cells.
    Klinman DM, Ishigatsubo Y, Steinberg AD.
    Cell Immunol. 1988 Dec;117(2):360-8.

    Pubmed

  • Acquisition and maturation of expressed B cell repertoires in normal and autoimmune mice.
    Klinman DM, Ishigatsubo Y, Steinberg AD.
    J Immunol. 1988 Aug 1;141(3):801-6.

    Pubmed

  • Autoantibody production is associated with polyclonal B cell activation in autoimmune mice which express the lpr or gld genes.
    Ishigatsubo Y, Steinberg AD, Klinman DM.
    Eur J Immunol. 1988 Jul;18(7):1089-93.

    Pubmed

  • Transfer of anti-DNA-producing B cells from NZB to unmanipulated xid recipients: effects of age, sex, and environment.
    Ishigatsubo Y, Klinman DM, Steinberg AD.
    Clin Immunol Immunopathol. 1987 Nov;45(2):244-51.

    Pubmed

  • Oncogene expression in autoimmune and normal peripheral blood mononuclear cells.                                                                    
    Klinman DM, Mushinski JF, Honda M, Ishigatsubo Y, Mountz JD, Raveche ES, Steinberg AD.
    J Exp Med. 1986 May 1;163(5):1292-307.

    Pubmed

  • Abnormalities of third-order suppressor T cells in old (New Zealand black x New Zealand white) F1 mice.
    Okuda K, Nagaoka S, Katoh K, Matsunaga K, Ishigatsubo Y, Minami M, Tani K.
    Immunology. 1984 Nov;53(3):553-61.

    Pubmed

  • Genetic control of contract hypersensitivity. II. Suppressor cells induced by intravenous injection of DNP-coupled syngeneic spleen cells possessing thy-1 antigen, I-J determinant, Lyt-2+, 3+ antigen, FcR- and DNP-membrane binding receptor on their surfaces.
    Ishii N, Ikezawa Z, Nagai R, Tani K, Ishigatsubo Y, Okuda K.
    Microbiol Immunol. 1981;25(1):63-70.

    Pubmed

  • Genetic control of contact hypersensitivity. I. I-A subregion as well as non-H-2 loci codes for the gene of 2,4-dinitro-1-fluorobenzene antigen.
    Okuda K, Ishii N, Ikezawa Z, Tani K, Ishigatsubo Y.
    Eur J Immunol. 1980 Dec;10(12):969-71.

    Pubmed

  • Antigen-pulsed neutrophils bearing Ia antigens can induce T lymphocyte proliferative response to the syngeneic or semisyngeneic antigen-primed T lymphocytes.
    Okuda K, Tani K, Ishigatsubo Y, Yokota S, David CS.  
    Transplantation. 1980 Nov;30(5):368-72.

    Pubmed

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